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Thalassemia Disorder

Thalassemia, a haemoglobin chain abnormality in which the red blood cells do not form properly and cannot carry sufficient oxygen begins during childhood and lasts throughout the life. Thalassemia is the most commonly inherited single gene disorder in the world. The genetic defect results in synthesis of an abnormal hemoglobin molecule. The blood cells are vulnerable to mechanical injury and die easily. Early comprehensive treatment has changed Thalassemia from a fatal pediatric disease to one in which patients live productive lives throughout adulthood.

Thalassemia Disorder Can Be Prevented

Thalassemia is an inherited single gene disorder condition. The gene received from one’s parents before birth determine whether a person will have Thalassemia or not. Thalassemia cannot be caught or passed on to another person. The genes involved in Thalassemia, control the production of a protein in the red blood cells called haemoglobin. Haemoglobin binds oxygen and carries it to the lungs and releases it when the red cells reach peripheral tissues, such as the liver. The binding and release of oxygen by haemoglobin is essential for survival. It is the defect in the formation of haemoglobin that leads to Thalassemia. Thalassemia, classified as a hemoglobinopathy, is characterized by the fact that the causative mutations result in a decrease in the amount of normal hemoglobin. .. Read More ...

Advances in treatment of Thalassemia disorder are exciting, resulting in the potential for cure and improved quality of life.

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